Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLTKLLTYLTTEPSVNDSQDPEITSIEMDSREVKKGSLFVCVKGYTVDGHDFAQKAVENGAAAIVAEREVDVNVPVIIVRQSLRALSVLSDAFYGQPTKKLQLIGITGTNGKTSTTHMVDEILKKAGKRTGLIGTMYMKI-------GDE-TLP-------------VKNTTPESVTLQKT--FKKMNDKHVDTAIMEVSSHALSLGRVHGCDYDIAVFTNLTQDHLDYHK-TMDEYRHAKSLLFSQLGGAFNHEHPKRAVLNADD-EA-SAYFEKVTAAH------ISTYGIKNDADVMAKNISITAQGTSFDLVTNKGTKH-ITMSLVGQFNVYNVLAAVATCIA--AGI-PFEIITEAVEELHGVRGRFELVNQQQEFPVIVDYAHTPDSLENVLETCRDM-TEGKLFVVVGCGGDRDKTKRPKMAKIAVELADEPIFTS-DNPRSEDPRAILRDMEAGVENAYYHSIANREQAIFFAIANAKKGDVVLIAGKGHETYQQIGNETFDFDDAEVAARAIVELNKNKTNS 3NRS Chain:A ((46-427)) -----------------------------------------------------------------------------------------------DLLKPAPKIFTVAGTNGKGTTCCTLEAILLAAGLRVGVYSSPHLLRYTERVRIQGQELSEAEHSHSFAQIEAGRGDISLTYFEFGTLSALQLFKQAKLDVVILEVGLGGR-LDATNIVDSDVAAITSIALDHTDWLGYDRESIGREKAGVFRGG---------KPAVVGEPDMPQSIADVAAELGAQLYRRDVAWKFSQ---------------NGWHWQCG----ERQLTGLPVPN-VPLANAATALAVLHYSELPLSD-EAIRQGLQAA-SLPGRFQVVSE--QPLLILDVAHNPHAARYLVNRLAQVI--GKVRAVVGMLSDKD---IAGTLACLSERVDEWYCAPLEGPRGASAGQLAEHLV------SARQFSDVETAWRQAMQDADTQDVVIVCGSFHT--------------------------------

General information: TITO was launched using: RESULT: Template: 3NRS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1825 -177797 -97.42 -552.16 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -97.42 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.443

(partial model without unconserved sides chains): PDB file : Tito_3NRS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3NRS-query.scw PDB file : Tito_Scwrl_3NRS.pdb: