Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSNEDMEQDNTTLLTEFVLTGLTYQPE------WKMPLFLVFLVIYLITIVWNLGLIALIWNDPQLHI-----PMYFFLGSLAFVDAWISSTVTPKMLVN----------FLAKNRMISLSECMIQFFSFAFGGTTECFLLATMAYDRYVAICKPLLYPVIMNNSLCIRLLAFS------FLGGFLHALI------------HEVLIFRLTFCNS----------------NIIHHFYCDIIPLFMISCTDPSINF-----------------------------------LMVFILSGSIQVFTIVTVLNSYTFALFTILKKKSVRG------VRKAFSTCGAHLLSVSLYYGP---------------LIFMYLRPASPQADDQDMIDS----------VFYTIIIPL-LNPIIYSLRNKQVIDSFTKMVKRNV-------------- 2W45 Chain:A ((7-466)) -LEDPMEEMTSYTFARFLRSPETEAFVRNLDRPPQMPAMRFVYLYCLCKQIQEFSGETGFCDFVSSLVQEDGPSLKSIYWGLQEATDEQRTVLCSYVESMTRGQSENLMWDILRNGIISSSKLLSTIKNGPTKVFEPAFGGPVAFGLRCEDTVKDIVCKLICGDASANRQFGFMISPTDGIFGVSLDLCVNVESQGDFILFTDRSCIYEIKCRFKYLFSKSEFDPIYPSYTALYKRPCKRSFIRFINSIARPTVEYVPDGRLPSEGDYLLTQDEAWNLKDVRKRKLGPGHDLVADSLAANRGVESMLYVMTDPSENAGRIGIKDRVPVNIFINPRHNYFYQVLLQYKIVGDYVRHSGGGKPGRDCSPRVNIVTAFFRKRSPLDPATCTLGSDLLLDASVEIPVAVLVTPVVLPDSVIRKTLSTAAGSWKAYADNTFDTAPWVPSGLFADD

General information: TITO was launched using: RESULT: Template: 2W45.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -291269 for 2181 contacts (-133.5/contact) + 2D Compatibility (PS) -31930 + (NN) 569 + (LL) 208 1D Compatibility (HY) -8800 + (ID) 2050 Total energy: -333272.0 ( -152.81 by residue) QMean score : 0.153

(partial model without unconserved sides chains): PDB file : Tito_2W45.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2W45-query.scw PDB file : Tito_Scwrl_2W45.pdb: