Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKEMTGLHSLVSIENFIKQHKFSFIYISRPGCTVCHAVLPQLRIVLDQFP-NIKLGHINADDVAEVAGRFSVFTVPVLLLFIDGTEFLREARFVHFEQLEQKLKRVYRLYEGE 2YZU Chain:A ((9-106)) ---------DQNFDETLGQHPLVLVDFWAEWCAPCRMIAPILEEIAKEYEGKLLVAKLDVDENPKTAMRYRVMSIPTVILFKDGQPVEVLVGAQPKRNYQAKIEKHL------

General information: TITO was launched using: RESULT: Template: 2YZU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 402 -89237 -221.98 -919.96 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -221.98 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.572

(partial model without unconserved sides chains): PDB file : Tito_2YZU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YZU-query.scw PDB file : Tito_Scwrl_2YZU.pdb: