Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLIEHYVALVKTGCAEYGQMNEMTLTEIADCLFCTERNAKLILHKLENSNWIIRESGAGRGRKSKIAFLRRPEELLLQTAKEYTMSGKLKKAKELLQQYQSAFPGLQNEYNMWLSEVFGFVTETGENGAKDVLRLFITPESVSSLDPCQIFLRSEGHFVKQIFDTLFTFDSDMQEPKPHLVHGWEEVGKKQWRFFLRKGVLFHNGQPLTSRDVAFTFQRFLELA-DNPYKWL--L---------------HGVKQVLEKGPYCVELILDKPNALLPYALCDERLSILPAEQG----------GGKNGTGPFQMNQQH-SGMLVLEANERYFKG-RPYLDRVEFVFSEQAGE-MN---GFTIQ-E----K--------QTCPEQQTVFDERHVQYLSLNLKKKGPLQHRSFRKALRLLISSERLVREAGGHRRIPVTSFLHPSP--------------FEWEGVSPSELLKKSGYE-GETIV--LYTFSETDHREDAEWIQNICA-QHGIRLTLQFCDAADLRRPEIVQMADIIHDSATFYQDSEFGFLHLLLSENSFL-YQHLSEKLTQICSGMTERMFSMPDRCSRINILRDIDRQMIQELNAIPLYQNVLQVTSSKNVKGLVL-DEEGWIDLYSVWLSK 1JET Chain:A ((10-516)) --------------------------------------------------------------------------------------------------------------------------------ADKQTLVRNN-GSEVQSLDPHKIEGVPESNVSRDLFEGLLISDV-EGHPSPGVAEKWENKDFKVWTFHLRENAKWSDGTPVTAHDFVYSWQRLADPNTASPYASYLQYGHIANIDDIIAGKKPATDLGVKALDDHTFEVTLSEPVPYFYKLLVHPSVSPVPKSAVEKFGDKWTQPANIVTNGAYKLKNWVVNERIVLERNPQYWDNAKTVINQVTYLPISSEVTDVNRYRSGEIDMTYNNMPIELFQKLKKEIPNEVRVDPYLCTYYYEINNQK-APFNDVRVRTALKLALDRDIIVNKVKNQGDLPAYSYTPPYTDGAKLVEPEWFKWSQQKRNEEAKKLLAEAGFTADKPLTFDLLYNTSDLHKKLAIAVASIWKKNLGVNVNLENQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTMLSDSSNNTAHYKS----PAFDKLIADTLKVADDTQRSELYAKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNIYVKNLYIIK

General information: TITO was launched using: RESULT: Template: 1JET.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2477 -159210 -64.28 -361.84 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -64.28 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.373

(partial model without unconserved sides chains): PDB file : Tito_1JET.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JET-query.scw PDB file : Tito_Scwrl_1JET.pdb: