Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MITMENIVRDGHPALRETAEPVELPPTDAEKQQLADMIEFVKNSQNPELAEKYKLRPGVGLAAPQINIKKRMIAVH-AEDASGKLYSYALFNPKIVSHSVEKSYLTSGEGCLSVDEAIPGY---VPRYARIRVKGTTLEGENIDIRLKGFPAIVFQHEIDHLNGVMFYDHIDKENPFKEPENAIAIER 1LRY Chain:A ((4-147)) -----NILEFPDPRLRTIAKPVEVV-DDAVRQLIDDMFETMYEA------------PGIGLAATQVNVHKRIVVMDLSEDKSE---PRVFINPEF--EPLTEDMDQYQEGCLSV----PGFYENVDRPQKVRIKALDRDGNPFEEVAEGLLAVCIQHECDHLNGKLFVDYL-----------------

General information: TITO was launched using: RESULT: Template: 1LRY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 682 -58917 -86.39 -420.83 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -86.39 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.388

(partial model without unconserved sides chains): PDB file : Tito_1LRY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1LRY-query.scw PDB file : Tito_Scwrl_1LRY.pdb: