Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLEQPIGVID-SGVGGLTVAKEIMRQLPKENIIYVGDTKRCPYGPR-PEEEVLQYTWELTNYLLENHHIKMLVIACNTATAIALDDIQRSVGIPVVGVIQPGARAAIKVTDNQHIGVIGTENTIKSNAYEEALLALNPDLKVENLACPLLVPFVESGKFLDKTADEIVKTSLYPLKDTSIDSLILGCTHYPILKEAIQRYMGEHVNIISSGDETAREVSTILSYKGLLNQSPIAPDHQFLTTGARDQFAKIADDWFGHEVGHVECISLQEPIKR 1B74 Chain:A ((1-252)) ---MKIGIFDSG-VGGLTVLKAIRNRYRKVDIVYLGDTARVPYGIRS-KDTIIRYSLECAGFLKDKG-VDIIVVACNTASAYALERLKKEINVPVFGVIEPGVKEALKKSRNKKIGVIGTPATVKSGAYQRKLEEGGADVFAKA--CPLFAPLAEEGLLEGEITRKVVEHYLKEFKG-KIDTLILGCTHYPLLKKEIKKFLGD-AEVVDSSEALSLSLHNFIKDDG-------SSSLELFFTDLSPNLQFLIKLILGRDYPVKLAEGVF-----

General information: TITO was launched using: RESULT: Template: 1B74.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1385 16254 11.74 65.01 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : 11.74 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.447

(partial model without unconserved sides chains): PDB file : Tito_1B74.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1B74-query.scw PDB file : Tito_Scwrl_1B74.pdb: