Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVTVREAKLEDIKDIAKVHVDSWRTTYHEIIPIDYLNSLNYKEFEDKWKSRS--LKGVFVAQDEKGSVFGFASFGPIRSEQEGYDGELYAIYLLEERQRQGAGRALLAKGAEFLLQHGFSSMFVWVI--EQN-PSIIFYQAYSPERVAEDNFEIA--GVRLKEVGLGWPDLSALKTLLNR 5DWM Chain:A ((9-177)) MPVIRDFQPADIETITAIYTQAVLTGTGSYEIE-P---PTMDEMAKRFAAFADQGFPILVAEA-DGRVLGYAYASYFRVRPAYRWLAEDSIYIAPDAKGQGIGKLLLRELIARISALGFRQLLAVIGDGEHNIGSVKLHESLGFTHCGRIEGSGFKHGRWLDTVLMQLPLNGGR------

General information: TITO was launched using: RESULT: Template: 5DWM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 747 -25070 -33.56 -154.75 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -33.56 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.446

(partial model without unconserved sides chains): PDB file : Tito_5DWM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DWM-query.scw PDB file : Tito_Scwrl_5DWM.pdb: