Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVLKRIRDMFVASVHEGLDKMENPKVMLNQYVRDMESDIAKAKQTIVKQHTIAYQFKKKYEEAAEVAGKRKNQAQLAFDAGEEELAKKALTEMKYLEGKAAEHKASYEQANSQLADLKEQLAALETKLQDVKDKKQALIARANAAKAKEHMNTTFDKIDSESAYREFLRIENRIEEMEIRANYSKSAEAGTELTRKEFADDVEAEIEKMRTLSLQKSDQTKAANE------- 1I6Z Chain:A ((85-219)) -------------------------------------------------------------------------------------------GSPEFMLIGEKSNPEEEVELKKLKDLEVSAEKIANHLQELNKELSGIQQGFLAKELQAEALCKLDR-KVKATIEQFMKILEEIDTMVLPEQF-----KDSRLKRKNLVKKVQVFLAECDTVEQYICQETERLQSTNLALAE

General information: TITO was launched using: RESULT: Template: 1I6Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 323 -13864 -42.92 -108.31 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -42.92 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.558

(partial model without unconserved sides chains): PDB file : Tito_1I6Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1I6Z-query.scw PDB file : Tito_Scwrl_1I6Z.pdb: