Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDIIFVCTGNTCRSPMAEALFKSIAEREG--LNVNVRSAGVFA-SPNGKATPHAVEALFEKHIALNHVSSPLTEELMESADLVLAMTHQHKQIIASQFGRYRDKVFTLKEYVTGSHGDVLDPFGGSIDIYKQTRDELEELLRQLAKQLKKDRR 2CWD Chain:A ((5-151)) VRVLFVCLGNICRSPMAEGIFRKLLKERGLEDRFEVDSAGTGAWHVGEPMDPRARRVLEEEGAYFPHVARRLTREDVLAYDHILVMDRENLEEVLRRFPEARGKVRLVLEELG--GGEVQDPYYGDLEDFREVYWTLEAALQAFLDRHG----

General information: TITO was launched using: RESULT: Template: 2CWD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 772 -9025 -11.69 -62.67 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -11.69 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.600

(partial model without unconserved sides chains): PDB file : Tito_2CWD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2CWD-query.scw PDB file : Tito_Scwrl_2CWD.pdb: