Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTPQPLADNL---SPPDPARLAQSIKDWGRELGFQQVGISDVELGEHEAHLQRWLEAGYHGEMDYMAAHGSKRSRPAELVPGTLRVISLRMDYLPGDTRMAQVLATPEKAYVSRYALGRDYHKLIRKRLQQLAERIQAEVGPFGFRAFVDSAPVLEKAIAEQAGLGWIGKNTLVLNRKAGSYFFLG--ELFVDMPLPVDPAMDSEHCGRCSACLDICPTAAFVGPYRLDARRCISYLTIEYKGAIPLELRPLIGNRVFGCDDCQIVCPWNRFARPTGQGDFQPRHSLDNAELAELFLWSEEEFLGRTEGSPLRRAGYERWLRNLAVGLGNAPSTIPVLEALKARRGFPSELVREHVEWALRRHGET 2NSY Chain:A ((1-271)) SMQEKIMRELHVKPSIDPKQEIEDRVNFLKQY-VKKTGAKGFVLG-----ISGGQDSTLAGRLAQLAVESIREEG------GDAQFIAVRL--PHGTQQDEDDAQLALKFIKPDKSWKFDIKSTVSAFSDQYQQETGDQ------LTDFNKGNVKARTRMIAQYAIGGQEGLLVLGTDHAAEAVTGFFTKYGDGGADLLP---------------------LTGLTKRQGRTLLKEL------GAPERLYL---------------------KEPTADLLDEKPQQSDETELGISYDEIDDYLEGKEVSAKVSEALEKRYSMT------------------EHKRQVPASMFDDWWK---------

General information: TITO was launched using: RESULT: Template: 2NSY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -18047 for 2121 contacts (-8.5/contact) + 2D Compatibility (PS) -28064 + (NN) -10388 + (LL) 5036 1D Compatibility (HY) 1200 + (ID) 1850 Total energy: -52113.0 ( -24.57 by residue) QMean score : 0.250

(partial model without unconserved sides chains): PDB file : Tito_2NSY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2NSY-query.scw PDB file : Tito_Scwrl_2NSY.pdb: