Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MWYNNSAGPFLLTGFLGSEAVHYRISMSFFVIYFSVLFGNGTLLVLI-WNDHSLHEPMYYFLAMLADTDLGMTFTTMPTVLGVLLLDQREIAHAACFTQSFIHSLAIVESGILLVLAYDCFIAIRTPLRYNCILTNSRVMNIGLGVLMRG---FMSILPIILSLYCYPYCGSRALLHTF--------CLHQDVIKLACADITFNHIYPIIQTSLTVFLDALIIIF--SYILILKTVMGIASGQEEAKSLNTCVSHISCVLVFHITVMGLSFIHRFGKHAPHVVPITMSYVHFLFPPFVNPIIYSIKTKQIQRSII---RLFSGQSRA 4LXU Chain:A ((1-273)) ----GHMIKICIAG-------KNNIAVNSLQFILKNYFEADQIVVIPNKNDKGIDSWQKSLLKFALDNNI--KIVTLDEIYNI-------------------------EQIIFFSLEFDQIIKIEN-------FKSDRLFNIHFSALPKYKGVFTSITPIL-----NNELESGVTLHRIDNGIDTGNIIDQHCFPIDINDTARDLYFNYLKYGESIFKKNIQTIINNSYKDLKQTNINSSYFSRKDINLVHKINFKKTSFEIHNQIR--AFI--FQEYQLPIINNSKIIKSILANEFIGYNVFEEFENYFIISGIDGFKIIAQKLNK

General information: TITO was launched using: RESULT: Template: 4LXU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -334378 for 1986 contacts (-168.4/contact) + 2D Compatibility (PS) -26706 + (NN) -1480 + (LL) 4844 1D Compatibility (HY) -16400 + (ID) 2150 Total energy: -376270.0 ( -189.46 by residue) QMean score : 0.205

(partial model without unconserved sides chains): PDB file : Tito_4LXU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4LXU-query.scw PDB file : Tito_Scwrl_4LXU.pdb: