Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVREAAMLHIKEGLEQEFEDAFRQAAPIISGMKGYITHSLSKCMEETHKYLLLVEWETLEDHTEGFRGSSEYQEWKALLHRFYTPFPTVEHFQDV 1X7V Chain:A ((6-96)) PLTLIATITAAPGHAEALERELRALVAPSRAEAGCLQYDLHQDRHDSHLFYMIEQWRDDAAL-ERHQNTEHFLRFSRGNEALLQN-VKIDQLY--

General information: TITO was launched using: RESULT: Template: 1X7V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 347 -35880 -103.40 -394.28 target 2D structure prediction score : 0.41 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -103.40 2D Compatibility (Sec. Struct. Predict.) : 0.41 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.429

(partial model without unconserved sides chains): PDB file : Tito_1X7V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1X7V-query.scw PDB file : Tito_Scwrl_1X7V.pdb: