Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVR-HAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF--FTAPLPAHPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 4BZD Chain:A ((2-295)) MENFQKVEKIGEG-YGVVYKARNKLTGEVVALKKIRL------VPSTAIREISLLKEL-NHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGL---------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY-KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4BZD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -188218 for 2125 contacts (-88.6/contact) + 2D Compatibility (PS) -28533 + (NN) -14642 + (LL) 2440 1D Compatibility (HY) -32400 + (ID) 6100 Total energy: -267453.0 ( -125.86 by residue) QMean score : 0.589

(partial model without unconserved sides chains): PDB file : Tito_4BZD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4BZD-query.scw PDB file : Tito_Scwrl_4BZD.pdb: