Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDTKQLKQDIIDYAYTIGIDSIGFTTADPFDELKQKLEAYHANGYASGFEESDIALRTEPKLSLPTARSIIAIAVGYPNKLKGAPKSVRGDRRGLFARASWGQDYHTIMRKRLDMLAAFIESKVPDVEIKSMVDTGVLSDRAVAERA-GLGFVGRNGFVINPKLGTWTYLGEMLVSIPFEPDDPLLDSCGDCTICVDRCPTSALVGNGQLNSQKCISFLTQTKGYMPDQYRYKIGNRLYGCDTCQQVCPKNRGINTEQDDIILEPEILKPRLVPLLRMSNKEFKQTYGHLAGAWRGKKPIQRNAIL-ALAHFNEVDAIPELKKVA-TTDERPMIRATAYWAIGQILGEEARDFINANYDQEDAEVQNEMIKGLDTRRE--- 4D50 Chain:A ((1-290)) -------GPLGSMVTEQEVDAIGQTLVDPKQPLQARFRALFTLRGLGG------------------PGAIAWISQAFD-------------------------DDSALLKHELAYCLGQMQDARAIPMLVDVLQDTRQEPMVRHEAGEALGAIGD---------------PEVLEILKQYSSDPVIEVAETCQLAVRRLEWLQQHGGEPAAGPY------LSVDPAPP--------------------AEERDVGRLREALLDESRPLFERYRAMFALRNAGGEEAALALAEGLHCGSALFRHEVGYVLGQLQHEAAVPQLAAALARCTENPMVRHECAEALGAIARPACLAALQAHADDPERVVRESCEVALDMYEHETG

General information: TITO was launched using: RESULT: Template: 4D50.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -19321 for 2421 contacts (-8.0/contact) + 2D Compatibility (PS) -30255 + (NN) -10171 + (LL) 5156 1D Compatibility (HY) -6000 + (ID) 2500 Total energy: -63091.0 ( -26.06 by residue) QMean score : 0.208

(partial model without unconserved sides chains): PDB file : Tito_4D50.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4D50-query.scw PDB file : Tito_Scwrl_4D50.pdb: