Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNRQELITEALKARDMAYAPYSKFQVGAALLTKDGKVYRGCNIENAAYSMCNCAERTALFKAVSEGDTEFQMLAVAADTPGPVSPCGACRQVISELCTKDVIVVLTNLQGQIKEMTVEELLPGAFSSEDLHDERKL 4F3W Chain:B ((8-126)) IDWKQLRDKATQVAAGAYAPYSRFPVGAAALVDDGRVVTGCNVENVSYGLALCAECGVVCALHATGGGRLVALACVDGRGAPLMPCGRCRQLLFEHGGPELLV--DHLAGPRR---LGDLLPEP------------

General information: TITO was launched using: RESULT: Template: 4F3W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 621 -67925 -109.38 -570.80 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain B : 0.77 3D Compatibility (PKB) : -109.38 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.585

(partial model without unconserved sides chains): PDB file : Tito_4F3W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4F3W-query.scw PDB file : Tito_Scwrl_4F3W.pdb: