Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -MSGRISDRDIAAI--REGARIEDVVGDYVQ-LRRAGADSLKGLCPFHNEKSPSFHVR-------------PNHGH----------FHCFGCGEGGDVYAFIQKIEH-VSFVEAVELLADRIGHTISYTGAATSVQRDRGSRSRLLAANAAAAAFYAQALQSDEAAPARQYLTERSFDAA--------------------AARKFGCGFAPSGWDSLTKHLQRKGFEF-EELEAAGLSRQGRHGPMDRFHRRLLWPI-----------RTSAGEV------VGFGARRLFD--------------------------------------DDAMEAKY------VNTP-ETLLYKKSSVMFGID-------------------LAKRDIAKGHQAV-------VVEGYTDVMAMHLAGVTTAVASCGTAFGG------EHLAMLRRLMMD-DSFFRGELIYVFDG---DEAGRAAALKAFDG---EQKLAG--QSFVAVAPDG--MDPCDLRLKCGDA------------ALR------DLVARRTPLFEFAIRAAIAEMDLDSAEGRVAALRRCVPMVGQIKDPTLRDEYARQLAGWVGWADVAQVIGRVRG-EAKRTKHPRLG--RLGSTTIARAAQRP---TAGPPTELAVRPDPRDPTLWPQREALKS---ALQYPALAGPVFD------------ALTV---EGFTHPEYAAVRAAIDTAGG------------TSAGLSGAQWLDMVRQQTTSTVTSALISELG---VEAIQVDDDK----------LPRYIAGVLARLQEVWLGRQIAEVKSKLQRMSPIEQGDEYHALFGDLVAM---------EAYRR-SLLEQASGDDLTA-------------- 4TUU Chain:A ((107-1046)) NREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLYQG--KYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRKSLWVINSALRIKILCATYV-NVNDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRAC--GMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDRVPFVLTQDFLIVISTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDA

General information: TITO was launched using: RESULT: Template: 4TUU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -88093 for 4190 contacts (-21.0/contact) + 2D Compatibility (PS) -67246 + (NN) -14804 + (LL) 792 1D Compatibility (HY) -30400 + (ID) 5450 Total energy: -205201.0 ( -48.97 by residue) QMean score : 0.164

(partial model without unconserved sides chains): PDB file : Tito_4TUU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4TUU-query.scw PDB file : Tito_Scwrl_4TUU.pdb: