Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRKLKIGITC---YPSVGGSGIIATELGKQLAEKGHEIHFITSSIPFRL-NTYHPNIHFHEVEVNQYAVFKYPPYDLTLASKIAEVAERENLDIIHAHYALPHAVCAYLAKQMLKRNIGIVTTLHGTDITVLGYDPSLKDLIRFAIESSDRVTAVSSALAAETYDLIKPEKKIETIYNFIDERVYLKKNT---AAIKEKHGILPDEKVVIHVSNFRKVKRVQDVIRVFRNIAG-KTKAKLLLVGDGPEKSTACELIRKYGLEDQVLMLGNQD--RVEDLYSISDLKLLLSE-------KESFGLVLLEAMACGVPCIGTNIGGIPEVIKNNVSGFLVDVGDVTAATARAMSILEDEQLSNRFTKAAIEMLENEFSSKKIVSQYEQIYADLAEPE 3OKP Chain:A ((4-380)) --SRKTLVVTNDFPPRIGGIQSYLRDFIATQD--PESIVVFASTQNAEEAHAYDKTLD---YEVIRWPRSVMLP-TPTTAHAMAEIIREREIDNVWFGAAAPLALMAGTAKQ--AGASKVIASTHGHEVGWSM-LPGSRQSLRKIGTEVDVLTYISQYTLRRFKSAFGSHPTFEHLPSGVDVKRFTPATPEDKSATRKKLGFTDTTPVIACNSRLVPRKGQDSLIKAMPQVIAARPDAQLLIVGSGRYESTLRRLATD--VSQNVKFLGRLEYQDMINTLAAADIFAMPARTRGGGLDVEGLGIVYLEAQACGVPVIAGTSGGAPETVTP-ATGLVVEGSDVDKLSELLIELLDDPIRRAAMGAAGRAHVEAEWSWEIMGERLTNILQSEP---

General information: TITO was launched using: RESULT: Template: 3OKP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1990 -25446 -12.79 -70.68 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -12.79 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.548

(partial model without unconserved sides chains): PDB file : Tito_3OKP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OKP-query.scw PDB file : Tito_Scwrl_3OKP.pdb: