Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence SVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAE 3MWU Chain:A ((18-281)) ----GTFAERYNIVCMLGKGSFGEVLKCKDRITQQEYAVKVINKASAK------NKDTSTILREVELLKKLDHPNIMKLFEILEDSSSFYIVGELYTGGELFDEIIKRKRFSEHDAARIIKQVFSGITYMHKHNIVHRDLKPENILLESKEKDCDIKIIDFGLSTCFQQN----DRIGTAYYIAPEVLR----GTYDEKCDVWSAGVILYILLSGTPPFYGK-NEYDILKRVETGKYAFDLPQWRTISDDAKDLIRKMLTFHPSLRITATQCLEHPWIQ--------------------------------------------

General information: TITO was launched using: RESULT: Template: 3MWU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -177566 for 2030 contacts (-87.5/contact) + 2D Compatibility (PS) -27669 + (NN) -14662 + (LL) 3584 1D Compatibility (HY) -24800 + (ID) 5200 Total energy: -246313.0 ( -121.34 by residue) QMean score : 0.394

(partial model without unconserved sides chains): PDB file : Tito_3MWU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3MWU-query.scw PDB file : Tito_Scwrl_3MWU.pdb: