Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSNENHEELNDQLIVRREK-VDTLREEGIDPFGEKFIRSISPEEIETKFADKSKEELEEAAIEVSVAGRIMTKRVKGK-VGFTHIQDRFHQLQIYIRKDAI--GEDAYAVFKLADLGDIIGIKGTIFRTNTGELSVKATEFTLLSKSLRPLPDKYHGLKDVEQRYRQRYLDLITNEESQNRFVMRSKILKYTRDYMDNQGFLEVETPVLHTIAGGAAAKPFITHHNALDMELYLRIALELHLKRLIVGGMDKVYEIGRVFRNEGTSTRHNPEFTMLESYAAYEDYEDVMDLVEGLVSTVCKQVN-GTTEITYGEYKVDLTPNWRRIHMADAVKEYVGVDFWNVTSDEEA----RELAKKHDVPVTEHMTYGHILNEFFETYVEEKLIQP---TFVYGHPVEISPLAKKNKEDERFTDRF---------------------------------------ELFIVGREHANAFSELNDPIDQRERFEAQMKEREQGNDEAHGMDADFLEALEYGLPPTGGLGIGIDRLVMLLTDAPSIRDILLFPTMKHRD 4UP7 Chain:A ((9-571)) --------LSKQLFLNRCKDVEEYQKAGHNPWPHKFNVSITVPEFIAKYSGLEKSQVSDDI--VSVAGRVLSKRSSSSALMFIDLHDSQTKLQIMLNKSAYENKEDFVSLTKMIYRGDICGFTGHPTRTKTGELSLIPISGMILSPCLHMLPSMHYGLGDQETRFRKRYLDLIVNPESVKNFVLRTKVVKAVRKYLDDKGFLEVETPILNTIPGGATARPFITHHNQLDIQMYMRIAPELYLKELVVGGINRVYEIGRLFRNEGIDQTHNPEFTTCEFYMAYADYNDIMKMTEELLGNMVKDITGGSTKLEIK------------------------------------FVTEKKMVLDFTAPF-KRISYVHALEEKFGEKIPRPLDGPEALTFLKKQAIRFNAICAEPQTTARVMDKLFGDLIEVDLVQPTFVCDQPQLMSPLAKYHRSEPELTERFELFILKREIANAYTELNNPIVQRSNFEQQAKDKAAGDDEAQLVDEVFLDAIEHAFPPTGGWGLGIDRLAMLLADVDNIKEVILFPTMRPED

General information: TITO was launched using: RESULT: Template: 4UP7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -110381 for 3227 contacts (-34.2/contact) + 2D Compatibility (PS) -47835 + (NN) -10795 + (LL) 3432 1D Compatibility (HY) -42400 + (ID) 10100 Total energy: -218079.0 ( -67.58 by residue) QMean score : 0.433

(partial model without unconserved sides chains): PDB file : Tito_4UP7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4UP7-query.scw PDB file : Tito_Scwrl_4UP7.pdb: