Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEIKGINHLLFSVSHLDTSIDFYQKVFGAK-LLVKGRTT------AYFDMNGIWLALNEEPDIPRNDIKLSYTHIAFTIEDHEFEEMSAKLKRLHVNILPGRERDERDRKSIYFTDPDGHKFEFHTGTLQDRLRYYKQEKTHMHFYDETAF 2P7Q Chain:B ((2-129)) --ISGLSHITLIVKDLNKTTAFLQNIFNAEEIYSSGDKTFSLSKEKFFLIAGLWICIMEGDSLQER----TYNHIAFQIQSEEVDEYTERIKALGVEMKPE-------GRSIYFYDFDNHLFELHAGTLEQRLK-----------------

General information: TITO was launched using: RESULT: Template: 2P7Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 435 272 0.62 2.38 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain B : 0.79 3D Compatibility (PKB) : 0.62 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.617

(partial model without unconserved sides chains): PDB file : Tito_2P7Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2P7Q-query.scw PDB file : Tito_Scwrl_2P7Q.pdb: