Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKHTFVLFLSLILLVLPGCSAEKSSADTAKKTLTIYSTMSTDSERDTFRKLAAAFEKEHSDIHVSLHF-PGNDYENMMRVRMAANDLPDLFDTH-G--WGKIRYGEYTADLRDMKW--TQDLDPNLNSILKNKSGKVYAYPINQAKDGLAYNRNILDRYGIAPPETMDDFIKALRTIKEKSKGSIVPFWFAGYDKSSFAQYYDQFATPLLITDPAHNEKKQLINGTFQW-S-KFTYLSEILKQMQKEKLINIDAVTAKKSQLIELMAQNKIAFTMQGGTLGQDVAQINPNVKVGIIPTPAIHPGDD-PIWIGGERYTLAAWKDSPQLKEAKDFIAFMARPANAKQMAEATSLPSG-LTNVKADIFYAND-YEYYQDVKVEP-YFDR---LYLPNGMWD-VLGTVGQELAADILAPQDISQKLGREYKRLREQSETQGAENNE 3OO8 Chain:A ((26-413)) ----------------------------GNGPITFGSNYSDEAPKAAFASLMQQATT-STTVPVTVNTTDHNTFQNNISNYLQ-GTPDSLATWFAGYRLQFFAAQGLLTPIDDVWDKIGGTFNDAAKSLSKGLDGHYYLVPLYNYPWVVFYNKSVFQSKGYEVPASWEAFIALARKMQ-S-DG-LVPLAFADKDGWPALGTFDILNLRI----NGYDYHIKLMKHEVPWTDPGVTKVFDQWRELAA--YQQKGANGRTWQDAAKALENKQAGMMFQGSNQVAANYSAKNLPDLDFFVFPAINPQYGTDYMD-APTDGFILPKKGKNAAAAKKVLQYIGTAEAEAAFLKTDHWDVGLANGLIAPT-YNDIQKKSVAEIGKCKSVSQFMERDTVP--DMANAMIKLIQQFIDQ-PTPETI-ATVQKSAEDQAKTI---------

General information: TITO was launched using: RESULT: Template: 3OO8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2073 38454 18.55 103.37 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 18.55 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.511

(partial model without unconserved sides chains): PDB file : Tito_3OO8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OO8-query.scw PDB file : Tito_Scwrl_3OO8.pdb: