Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKILVIDDHPAVMEGTKTILETDSNLS-VDCLSPEPSE-QFIKQHDFSSYDLILMDLNLGGEVNGMELSKQILQENPHCKIIVYTGYEVEDYFEEAIRAGLHGAISKTESKEKITQYIYHVLNGEILVDFAYFKQLMTQQKTKPAPSSQKEQDVLTPRECLILQEVEKGFTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDGVL 1A04 Chain:A ((8-215)) --TILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQGIELAE---SLDPDLILLDLNMPG-MNGLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALHQAAAGEMVLSEALTPVLAASL--------ERDVNQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERI-

General information: TITO was launched using: RESULT: Template: 1A04.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 981 21283 21.69 106.95 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : 21.69 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.432

(partial model without unconserved sides chains): PDB file : Tito_1A04.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1A04-query.scw PDB file : Tito_Scwrl_1A04.pdb: