Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGLSDWELAAARAAIARGLDEDLRYGPDVTTLATVPASATTTASLVTREAGVVAGLDVALLTLNEVLGTNGYRVLDRVEDGARVPPGEALMTLEAQTRGLLTAERTMLNLVGHLSGIATATAAWVDAVRGT--KAKIRDTRKTLPGLRALQKYAVRTGGGVNHRLGLGDAALIKDNHVAAAGSVVDALRAVRNAAP-DLPCEVEVDSLEQLDAVLPEKPELILLDNFAVWQTQTAVQRRDSRAPTVMLESSGGLSLQTAATYAETGVDYLAVGALTHSVRVLDIGLDM 4I9A Chain:B ((23-285)) ------------------LREDC---PGLNPVALVTGAAPSQAVLWAKSPGILAGRPF----FDAIFAQVNCQVSWFLPEGSKLVPVAKVAEVRGPAHCLLLGERVALNMLARCSGVASAAATAVETARGTGWAGHVAGTRKTTPGFRLVEKYGLLVGGATSHRYDLGGLVMVKDNHVVAAGGVKQAVQGARRAANFALKVEVECSSLQEALEAAEAGADLVLLDNFRPEELHPTAAALKAQFPTVGVEASGGVTLDNLPQFCGPHIDVISLGMLTQAAPALDFSLKL

General information: TITO was launched using: RESULT: Template: 4I9A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -133233 for 2176 contacts (-61.2/contact) + 2D Compatibility (PS) -27938 + (NN) -11278 + (LL) 2208 1D Compatibility (HY) -17600 + (ID) 4250 Total energy: -192091.0 ( -88.28 by residue) QMean score : 0.615

(partial model without unconserved sides chains): PDB file : Tito_4I9A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4I9A-query.scw PDB file : Tito_Scwrl_4I9A.pdb: