Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTP-SHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYV-TFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF 4BGH Chain:A ((2-298)) ---------ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKI------------PSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLA--------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------

General information: TITO was launched using: RESULT: Template: 4BGH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -190324 for 2127 contacts (-89.5/contact) + 2D Compatibility (PS) -28825 + (NN) -12096 + (LL) 4116 1D Compatibility (HY) -29600 + (ID) 6150 Total energy: -262879.0 ( -123.59 by residue) QMean score : 0.585

(partial model without unconserved sides chains): PDB file : Tito_4BGH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4BGH-query.scw PDB file : Tito_Scwrl_4BGH.pdb: