Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGLNTAIATRVNGTPPPEVPIADIELGSLDFWALDDDVRDGAFAT---LRREAPISFWPTIELPGFVAGNGHWALTKYDDVFYASRHPDIFSSYPNITINDQTPELAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEAAVRDRAHRLVSSMIANNPDRQADLVSELAGPLPLQIICDMMGIPKADHQRIFHWTNVILGFGDPDLATDFDEFMQVSADIGAYATALAEDRRVNHHDDLTSSLVE-AEVDGERLSSREIASFFILLVVAGNETTRNAITHGVLALSRYPEQRDRWWSDFDGLAPTAVEEIVRWASPV-VYMRRTLTQDIELRGTKMAAGDKVSLWYCSANRDESKFADPWTFDLARNPNPHLGFGGGGAHFCLGANLARREIRVAFDELRRQMPDVVATEEPARLL---SQFIHGIKTLPVTWS 2WI9 Chain:B ((35-425)) ----------------------------LDLGALGQDFAADPYPTYARLRAEGPAHRVRTPE------GNEVWLVVGYDRARAVLADPRFSKDWRNSTTPLTEAE-AALNHNMLESDPPRHTRLRKLVAREFTMRRVELLRPRVQEIVDGLVDAMLAA-PDGRADLMESLAWPLPITVISELLGVPEPDRAAFRVWTDAFVFPDDPAQA------QTAMAEMSGYLSRLIDSKRGQDGEDLLSALVRTSDEDGSRLTSEELLGMAHILLVAGHETTVNLIANGMYALLSHPDQLAALRADMT-LLDGAVEEMLRYEGPVESATYRFPVEPVDLDGTVIPAGDTVLVVLADAHRTPERFPDPHRFDIRRDTAGHLAF-GHGIHFCIGAPLARLEARIAVRALLERCPDLALDVSPGELVWYPNPMIRGLKALPIRW-

General information: TITO was launched using: RESULT: Template: 2WI9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -203964 for 3112 contacts (-65.5/contact) + 2D Compatibility (PS) -40550 + (NN) -12790 + (LL) 1436 1D Compatibility (HY) -23600 + (ID) 7000 Total energy: -286468.0 ( -92.05 by residue) QMean score : 0.396

(partial model without unconserved sides chains): PDB file : Tito_2WI9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2WI9-query.scw PDB file : Tito_Scwrl_2WI9.pdb: