Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSTSLPQAARSVRSSRSTTLTTTAVVLAGIAPLGNAAGFLEDSKASLETRNFYMNRDFRDGPGQSKREEWAQGFILNLQSGYTQGTVGFGLDAMGMLGVKLDSGRGRSGTGLLPKDSDGRAPDTYSKLG-LTAKVKVSQSELKVGTLIPKLPSVQPNNGRIFPQIFEGALLTSKEIKDLGFTAGRLEKTKIRDSSDSEDLALNDKNGRFAGVSADHFDLGGLDYKLT-DQLTASYHYSNLQDVYRQHFVGLLHSWPIGPGELTSDLRFARSTDSGSAKAGGIDNKSLNGMFTYSLGNHAFGAAWQRMNGDDAFPYLEGS-NPYLVNFVQVNDFAGPKERSWQLRYDYDFVGLGIPGLTFMTRYVKGDNVELAGQSGEGREWERNTELQYVFQSGALKNLGIRWRNATFRSNFTRDIDENRLIVSYTLPIW 2Y2X Chain:A ((4-390)) -------------------------------------GFLEDAKTDLVLRNYYFNRDF-------LVDEWAQGFILKFSSGYTPGTVGVGLDAIGLFGVKLNS-----NSELLPLHDDGRAADNYGRVGVA-AKLRVSASELKIGEMLPDIPLLRYDDGRLLPQTFRGFAVVSRELPGLALQAGRFDAVSLRNSADMQDLSAWSAP----TQKSDGFNYAGAEYRFNRERTQLGLWHGQLEDVYRQSYANLLHKQRVGDWTLGANLGLFVDRDDGAARAGEIDSHTVYGLFSAGIGLHTFYLGLQKVGGDSGWQSVYGSSGRSMGNDMFNGNFTNADERSWQVRYDYDFVGLGWPGLIGMVRYGHGSNATTKA-GSGGKEWERDVELGYTVQSGPLARLNVRLNHASNRRSFNSDFDQTRLVVSYPLSW-

General information: TITO was launched using: RESULT: Template: 2Y2X.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 11989 for 2976 contacts (4.0/contact) + 2D Compatibility (PS) -38334 + (NN) -6146 + (LL) 2552 1D Compatibility (HY) -30400 + (ID) 8050 Total energy: -68389.0 ( -22.98 by residue) QMean score : 0.176

(partial model without unconserved sides chains): PDB file : Tito_2Y2X.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Y2X-query.scw PDB file : Tito_Scwrl_2Y2X.pdb: