Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIAGSMVALVTPFDAQGRLDWDSLAKLVDFHLQEGTNAIVAVGTTGESATLDVEEHIQVIRRVVDQVKGRIPVIAGTGANSTREAVALTEAAKSGGADACLLVTPYYNKPTQEGMYQHFRHIAEAVAIPQILYNVPGRTSCDMLPETVERLSKVPNIIGIKEATGDLQRAKEVIERVGKDFLVYSGDDATAVELMLLGGKGNISVTANVAPRAMSDLCAAAMRGDAAAARAINDRLMPLHKALFIESNPIPVKWALHEMGLIPEG-IRLPLTWLSPRCHEPLRQAMRQTGVLA 4ICN Chain:B ((7-294)) MINGSIVALITPLNSDGTVDYTSLEKLVEYHITEGTDAIVAVGTTGESATLPISEHIAVVGQTVKFASGRIPVIGGNGANATAEAIELTKAQNKLGVAAMLGVTPYYNKPSPKGLIAHYTAVAASTDIPQILYNVPGRTAVDMLPETIAQLVEVPNIIGVKDATGDVARVKQLRDLCGNDFLLYSGDDATAREFLTLGGDGVISVANNIVPKLFKLMCDAALAGDTQAAMAAEDQIKGLFSALFCEANPIPVKWAAHKMGLISQGDIRLPLTELSTEFHGLLLDAMKNARIEV

General information: TITO was launched using: RESULT: Template: 4ICN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -187004 for 2553 contacts (-73.2/contact) + 2D Compatibility (PS) -32014 + (NN) -23412 + (LL) 0 1D Compatibility (HY) -30000 + (ID) 8150 Total energy: -280580.0 ( -109.90 by residue) QMean score : 0.605

(partial model without unconserved sides chains): PDB file : Tito_4ICN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ICN-query.scw PDB file : Tito_Scwrl_4ICN.pdb: