Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYKKFVPFAVFLFLFFVSFEMMENPHALDYIGAMKKDTVTVTASKDPLYEELLQKAPEYEVKPQNARIDKVWKSIPGYNGLKVNIEQSYKKMKQHGKFREKDLVYSQVKPSVHLESLQPEPIYKGNPDKPMVAFLINVAWGNEYLEKMLPILQKHQVKATFFLEGNWVRN-NVQLAKKIAKDGHEIGNHSYNHPDMSKLTTGRISEQLDKTNEQIEQTIGVKPKWFAPPSGSFRKAVIDIAAEKQMGTVMWTVDTIDWQKP-APSVLQTRVLSKIHNGAMILMHPTD----PTAESLEALITQIKDKGYALGTVTELMDETRLLK 2C71 Chain:A ((5-194)) ---------------------------------------------------------------------------------------------------------------------------------KLVALTFDDGPDNVLTARVLDKLDKYNVKATFMVVGQRVNDSTAAIIRRMVNSGHEIGNHSWSYSGMANMSPDQIRKSIADTNAVIQKYAGTTPKFFRPPNLETSPTLFNN---VDLV-FVGGLTANDWIPSTTAEQRAAAVINGVRDGTIILLHDVQPEPHPTPEALDIIIPTLKSRGYEFVTLTELFTLKGV--

General information: TITO was launched using: RESULT: Template: 2C71.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 991 -110211 -111.21 -598.97 target 2D structure prediction score : 0.79 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -111.21 2D Compatibility (Sec. Struct. Predict.) : 0.79 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.607

(partial model without unconserved sides chains): PDB file : Tito_2C71.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2C71-query.scw PDB file : Tito_Scwrl_2C71.pdb: