Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVNEKRLLEEFLELVQIDSETKHEAEICKVLKRKFSDLGVDVKEDDTMDITGHGAGNLICTLKGTKQTDTIYFTSHMDTVVPGNGVKPVVENGYVKTDGTTILGADDKAGLAAMFEAIKVLKEENIEHGTIEFIITVGEESGL-IGAKALDRSMITASYGYALDSDGKVGNIIVAAPTQAKVRAAIFGKTAHAGVEPEKGISAITIASKAISKMPLGRID--E---------ETTANIGRFEGGTQTNIVCDEVHILAEARSLVPEKMEAQVQKMKAAFEEAAADMGGRAEVEIEVMYPGFKYQDGDQVVEIAKKAAAKIGRPSELQTSGGGSDANVIA-GHGIPTVNLAVGY-EQIHTKNEKMPIEELVKTAEMVVAIIEEAAK 4Q7A Chain:A ((11-359)) --MSMTTADLLRGLVSIPSPSGAEAPAVEWLCQQMAALGYQAEPDG--------AGNAVGTRGE--GPREIMLLGHIDTVPGEVPV--QVVDGVLYGRGA----VDAKGPLATFVVAGARAKL--PPGVRLTVVGAVEEEVMSSRGARHLIATREAPDAVVIGEPSG-WDGVVLGYRGSVALEYRVTVPMSHSA-GPEA--TAAELAADFWYRLRTWCAEWSVGIDHAFHRVEPKLNA----LNSSSDGLYGEAVARIGLRLPPALSPEEAIAVATSLASEG------EVTAT--VNAPAFQTDKRQPIVAAFLAAVRAHGGTPRLKLKTGTSDMNLVGPAWGCPIVAYGPGDSRLDHTPEEHVPLADLERATAILTTAIERVAA

General information: TITO was launched using: RESULT: Template: 4Q7A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1936 -17588 -9.08 -52.50 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -9.08 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.449

(partial model without unconserved sides chains): PDB file : Tito_4Q7A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Q7A-query.scw PDB file : Tito_Scwrl_4Q7A.pdb: