Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRRIVVTGMGMINSLGLNKEDSFLAIAKGECGIKNIESFDANAFPVRIAGEIT------DFDPTEVMNPKDVKKAGRFIQLALKATREAMKDSGILDAHNRCPEELANRM--GVSSGSGIGGLGNIEANSIFCFEKGPRKVNPFFITSALVNMIGGFTSIEFGIKGPNLSSVTACAAGTHAIIEAVKTILLNGADRMLVVGAESTICPVGIGGFASIKALSTRNDDPKKASRPFDKDRNGFVMGEGAGALVLEEYESAKKRGAKIYAEFAGYGESGDANHITAPAPEGEGAFRAMKMALEMAKV---EVGYVNAHGTSTHYNDWYESIALKNVFGSKEKVPPVSSTKGQIGHCLGAAGALEAVISIMAMNQGILPPTINQETPDPECDLDYIPNTAREKQVNAV---MSNSFGFGGTNGVVIFKKA 2IWZ Chain:A ((21-433)) -RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWH------PQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL

General information: TITO was launched using: RESULT: Template: 2IWZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -130902 for 3856 contacts (-33.9/contact) + 2D Compatibility (PS) -42156 + (NN) -17300 + (LL) 496 1D Compatibility (HY) -24000 + (ID) 8850 Total energy: -222712.0 ( -57.76 by residue) QMean score : 0.429

(partial model without unconserved sides chains): PDB file : Tito_2IWZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IWZ-query.scw PDB file : Tito_Scwrl_2IWZ.pdb: