Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKIVVALGGNALGNSPE---EQLRLVKHTAKSLVALIKKGHEIVVSHGNGPQVGAINLGMNFA-AE-SGQGTNFPFPECGAMSQGYIGYHLQQSLLNELRQEGINKEVATIITQIEVDESDQAFSAPTKPIGTFYDKE-------TSEK--IAIEKGY---TFVEDAGRGYRRVVASPEPKKIIE---INSIKTLIENDTLVIAGGGGGIPVIN---KGGYEGIAAVIDKDKSSALLAGELAADQLIILTAVDYVYTQFGKENQKALTEVNENQMIDYVNQGEFAKGSMLPKVIACMSFLDHNPKGTALITSLN-GLEDALDGK-LGTRITK 2WE5 Chain:A ((2-310)) GKKMVVALGGNAILSNDASAHAQQQALVQTSAYLVHLIKQGHRLIVSHGNGPQVGNLLLQQQAADSEKNPAMPLD--TCVAMT-QGSIGYWLSNALNQELNKAGIKKQVATVLTQVVVDPADEAFKNPTKPIGPFLTEAEAKEAMQAGAIFKEDAGRGWRKVVPS----------------PKPIDIHEAETINTLIKNDIITISCGGGGIPVVGQELKGVEAV----IDKDFASEKLAELVDADALVILTGVDYVCINYGKPDEKQLTNVTVAELEEYKQAGHFAPGSMLPKIEAAIQFVESQP-NKQAIITSLENLGSMSGDEIVGTVVTK

General information: TITO was launched using: RESULT: Template: 2WE5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -112533 for 2310 contacts (-48.7/contact) + 2D Compatibility (PS) -31003 + (NN) -13523 + (LL) 1256 1D Compatibility (HY) -17600 + (ID) 6050 Total energy: -179453.0 ( -77.69 by residue) QMean score : 0.506

(partial model without unconserved sides chains): PDB file : Tito_2WE5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2WE5-query.scw PDB file : Tito_Scwrl_2WE5.pdb: