Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIGVIDYGMGNLYSVSKALERVGVPYFVSEKPEELKEADAFILPGVGSFGDAMDNLGYTKLDQLIHDMVSEGRLLLGICLGMQLLFEESEENGTASGLGLLKGKAVRLKAEDEKGNKLKVPHMGWNRLSFHNESPLLTKTE-QGYAYFVHSYYIDGMEE-NALLASADYGVRVPAVVGKRNVFGAQFHPEKSSTVGMSILTQFTKMAAEQKVKK 1Q7R Chain:A ((25-214)) KIGVLGLQ-GAVREHVRAIEACGAEAVIVKKSEQLEGLDGLVLPGGESTTMR-RLIDRYGLMEPLKQFAAAGKPMFGTCAGLILLAKRIVGY-DEPHLGLMDITVERNSF-------------GRQRE-SFEAELSIKGVGDGFVGVFIRAPHIVEAGDGVDVLATYNDR---IVAARQGQFLGCSFHPELTDDH--RLMQYFLNMVKEAKM--

General information: TITO was launched using: RESULT: Template: 1Q7R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1071 -89460 -83.53 -475.85 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -83.53 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.444

(partial model without unconserved sides chains): PDB file : Tito_1Q7R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Q7R-query.scw PDB file : Tito_Scwrl_1Q7R.pdb: