Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRKLKIGITCY---PS--VGGSGIIATELGKQLAEKGHEIHFITSSIPFRLNTYH----------------------PNIHFHEVEVNQ--------YA---VFKYP----PYD---LTLASKIAEVAERENLDIIHAHYALPHAVCAYLAKQMLKRNIGIVTTLHGTDITVLGYD--------------------PSLKDLIRFAIESSDRVTAVSSALAAETYDLI---K---------PEKKIETIYNFIDERVYLKKNT-------------------AAIKEKHGI--LPDEKVVIHVSNFRKVKRVQDVIRVFRNIAGKTKAKLLLVGDGPE--KSTACELIRKYGLEDQVLMLGNQD-RVEDLYSISDLKLLLSEKESFGLVLLEAMACGVPCIGTNIGGIPEVIKNN---------VSGFLVDVGDVTAATARAMSILE---DEQLSNRFTKAAIEMLENEFSSKKIVSQYEQIYADLAEPE 2QZS Chain:A ((1-477)) ---MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAFPDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFAYTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAAR--GRPAKSVFTVHNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYAREITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAENKRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLE-QGGQLALLGAGDPVLQEGFLAAAAEYPGQVGV-QIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRFVQR---QAMAMDFSWQVAAKSYRELYYRLK---

General information: TITO was launched using: RESULT: Template: 2QZS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1942 -13713 -7.06 -37.67 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -7.06 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.488

(partial model without unconserved sides chains): PDB file : Tito_2QZS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QZS-query.scw PDB file : Tito_Scwrl_2QZS.pdb: