Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MELYIITGASKGLGQAIALQALEKGHEVHALSRTKTD---V----SH---K-KLTQHQIDLINLEEAEQQFETLLSSIDSDRYSGITLINNAGMVTPIKRA-GEASLDELQRHYQLNLTAPVLLSQLFTKRFASYS-GKKTVVNITSGAAKNPYKGWSAYCSSKAGLDMFTRTFGFEQEDEELPVNMISFSPGVMDTEMQAVIRSSSKKDFHHIERFRKLNETGS-LRSPDFIAGTLLSLLEKG--TENGRIYDIKEFL 1MXH Chain:A ((11-269)) CPAAVITGGARRIGHSIAVRLHQQGFRVVVHYRHSEGAAQRLVAELNAARAGSAVLCKGDLSLSSSLLDCCEDIIDCSFRAFGRCDVLVNNASAYYPTPLLP--PIDAQVAELFGSNAVAPLFLIRAFARRQ----SRNLSVVNLCDAMTDLPLPGFCVYTMAKHALGGLTRAAALELA--PRHIRVNAVAPGLSLLPPAMPQETQ--------EEYRRKVPLGQSEASAAQIADAIAFLVSKDAGYITGTTLKVDG--

General information: TITO was launched using: RESULT: Template: 1MXH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1161 -14282 -12.30 -63.48 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -12.30 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.457

(partial model without unconserved sides chains): PDB file : Tito_1MXH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1MXH-query.scw PDB file : Tito_Scwrl_1MXH.pdb: