Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKVLVTGAGGQLGLELCRQLKQAGYEVIALTKKMMNIADQRSVRHSFGHY--QPDIVVNSAAFTSVDQCE--K-E-LD-KAYLINGIGAYYTALESTRIGAQYVHISTDYVFNGKGTQPYREDDPLDPKTIYGKSKRLGEELIRLTTKDSTIIRTSWVYGHGGSNFVETMLKLAETKQELRVVSDQIGSPTYTKDLAEAVIKLFSH-PPGIYHVSNSGICSWYEFATAIMEESGLETAILSVTTEEYGNKTPRPAYSVLSHRAIEE-AGI-RPRHWREALREYLQERSSACD 3SC6 Chain:A ((5-285)) KERVIITGANGQLGKQLQEELNPEEYDIYPFDKKLLDITNISQVQQV--VQEIRPHIIIHCAAYTKVDQAEKERDLAYVINAIGARNV---AVASQL--VGAKLVYISTDYVFQGDRPEGYDEFHNPAPINIYGASKYAGEQFVKELHNKYFIVRTSWLYGKYGNNFVKTMIRLGKEREEISVVADQIGSPTYVADLNVMINKLIHTSLYGTYHVSNTGSCSWFEFAKKIFSYANMKVNVLPVSTEEFGAAAARPKYSIFQ-HNMLRLNGFLQMPSWEEGLERFFIETK----

General information: TITO was launched using: RESULT: Template: 3SC6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1529 -34183 -22.36 -126.14 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -22.36 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.528

(partial model without unconserved sides chains): PDB file : Tito_3SC6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3SC6-query.scw PDB file : Tito_Scwrl_3SC6.pdb: