Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLPKPNNQTTVVITGASSGIGVELARGLAGRGFPLMLVARRRERLDELADQLRQEHCVGVEVLPLDLADTQARAQLADRL-----RSDAIAGLCNSAGFGTSGRFWELPFARESEEVVLNALALMELTHAALP--GMVKRGAGAVLNIASIAGFQPIPYMAVYSATKAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWA-----------EIASAERFS-----IPLAQ-VSPHDVAEAAIAGMLSGKRTVVPGIVPKFVSTSGRFAPRSLLLPAIRIGNRLRGGPSR 4DC1 Chain:B ((24-254)) ------QDSEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELRE---AGVEA-DGRTCDVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFRVTKQVLKAGGMLERGTGRIVNIASTGGKQGVVHAAPYSASKHGVVGFTKALGLELARTGITVNAVCPGFVETPMAASVREHFSDIWEVSTEEAFDRITARVPIGRYVQPSEVAE--------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4DC1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -124860 for 1669 contacts (-74.8/contact) + 2D Compatibility (PS) -22920 + (NN) -13458 + (LL) 2984 1D Compatibility (HY) -12000 + (ID) 3700 Total energy: -173954.0 ( -104.23 by residue) QMean score : 0.548

(partial model without unconserved sides chains): PDB file : Tito_4DC1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4DC1-query.scw PDB file : Tito_Scwrl_4DC1.pdb: