Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFMFEKPHGMRDTLPGLYETKKKVRRSLTDLIDKWGYQFMETPTLEFYDTVGVQSAIEEQQLFKLLDQDGKTLVLRPDMTGPIARVAASKLLKHGHPLRVGYAANVFRAQEREGGRPAEFEQVGVELIGDGTTSADAEVIALVVGALKNAGLASFKIAIGHAGIADALFVEVLGNVERADVLRRFLYEKNYVGYREH-VKSLPLSSIDKSRLLELLELRGGIEVCGRAEEIVDSAQGKSVVDELKALWDILEDYGCTENVRLDLNMVSHMSYYTGILFEVYAENVGFVIGSGGRYNKLLGHFDSPAPATGFGLRIDRLIEALHMKDEPC-EIDAVIFSKEQRAQ-AIAYANEERMKGNKVVLQDLSGIENIDQMTKSFANVTYFIGARKEEQNG 3OD1 Chain:A ((8-373)) -FMFEKPFGMRDTLPEWYKTKKNICDQMTEEINLWGYDMIETPTLEYYETVGVVSAILDQQLFKLLDQQGNTLVLRPDMTAPIARLVASSLKDRAYPLRLAYQSNVYRAQQ---GKPAEFEQLGVELIGDGTASADGEVIALMIAALKRAGLSEFKVAIGHVGYVNALLMDVVGNEQRADRLRRFLYEKNYVGYREHVKSL-NLSTIDKSRLMNLLSLRGGRAAIEEARGLIQTEKGKTALAEMTKLYEVLESYGASEYVKFDLTLVLHMSYYTGVVFEGYGNRLGVPLCSGGRYDELLSKFHRPAQATGFGVRIDLLVEALN-----GHEQTCILF-SNERRFEAIELARKKRANGEAVVLQDLAGV--------------------------

General information: TITO was launched using: RESULT: Template: 3OD1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1694 -98353 -58.06 -277.83 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.88 3D Compatibility (PKB) : -58.06 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.88 QMean score : 0.541

(partial model without unconserved sides chains): PDB file : Tito_3OD1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OD1-query.scw PDB file : Tito_Scwrl_3OD1.pdb: