Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQGLLTSGRKPSGGGRCTGRGGWRGQWCLKPWMGGADPPTPTLSCLLLPVPPELPDHCYRMNSSPAGTPSPQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQR-ERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTF-CGTPEYLAPEVLRKE-----PYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQP--LQIPGG---RTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKSIGCTPDTVASSSGASSAFLGFSYAPEDDDILDC 3TKU Chain:B ((86-423)) ----------------------------------------------------------------------------------------QLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLV-NGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICS-RERRLGQNG-IEDFKKHAFFEGLNWENI--RNLEAPYIPDVSSPSDTSNFD---------------------FSGLHLPFIGFTFTTESCFSDRG

General information: TITO was launched using: RESULT: Template: 3TKU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -181592 for 2486 contacts (-73.0/contact) + 2D Compatibility (PS) -33220 + (NN) -22653 + (LL) 1224 1D Compatibility (HY) -30800 + (ID) 5850 Total energy: -272891.0 ( -109.77 by residue) QMean score : 0.529

(partial model without unconserved sides chains): PDB file : Tito_3TKU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TKU-query.scw PDB file : Tito_Scwrl_3TKU.pdb: