Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFD---DTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT 3TKH Chain:A ((9-264)) ------------------------WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIV----------N--IKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVF-------------RYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTS--------------------

General information: TITO was launched using: RESULT: Template: 3TKH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -141472 for 1902 contacts (-74.4/contact) + 2D Compatibility (PS) -24960 + (NN) -665 + (LL) 3604 1D Compatibility (HY) -15600 + (ID) 4150 Total energy: -183243.0 ( -96.34 by residue) QMean score : 0.366

(partial model without unconserved sides chains): PDB file : Tito_3TKH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TKH-query.scw PDB file : Tito_Scwrl_3TKH.pdb: