Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLPLHISLEKKKVVIAGGGSIALRRLKTVISEGADITLVSPDVEPEIKQMAE--ERRIKWEKRTIE------KEDYLNAFFIIAATDNAAVNKEIAQSASP-F---QLVNCVSDAELGNVYMPKIVKRGHVTVSVSTSGASPKHTKELAENVDKLIDGDFVAEVNRLYQMRRKK 1ID1 Chain:A ((4-139)) --------RKDHFIVCGHSILAINTILQLNQRGQNVTVISNLPEDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSDNDADNAFVVLSAKDMSSDVKTVLAVSDSKNLNKIK-----MVHPDIILSP---QLFGSEILARVL----------------------

General information: TITO was launched using: RESULT: Template: 1ID1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 562 -61046 -108.62 -492.30 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -108.62 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.556

(partial model without unconserved sides chains): PDB file : Tito_1ID1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ID1-query.scw PDB file : Tito_Scwrl_1ID1.pdb: