Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRKRKLGTSDLDISEVGLGCMSLGTE---KNKALSILDEAIELGINYLDTADLYDRGRNEEIVGDAIQNRRHDIILATKAGNRWDDGSEGWYWDPSKAYIKEAVKKSLTRLKTDYIDLYQLHGGTIEDNIDETIEAFEELKQEGVIRYYGISSIRPNVIKEYVK---KSNIVSIMMQFSLFDRRPEE-WLPLLEEHQISVVARGPVAKGLLTEKPLDQASESMKQNGYLSYSFEELTNARKAMEEVA--PDLSMTEKSLQYLLAQPAVASVITGASKIEQLRENIQAANARRLTEEEIKALQSHTKQDIYKAHRS 5C7H Chain:A ((5-275)) IPTIAFP-DGRKVPALGQGTWRMGENRAKTADEVRSLQTGLDLGMTLIDTAEMYGDGAAERIVGEAIKGRRDEAFVVSKVLPS----------NASRAGTVAACERSLRNLGIDCVDLYLLHWRGGY-PLAETVAAFEELKKAGKIRAWGVSNFDVDDMEELSAVPDGGNVAANQVLYNLARRGIEFDLLPRCRAQGVPVMAYSPLDEGRLLHDA--------------------------DLIHIAKAHQATPAQVALAFLKTCSGV-ISIPKTGSPERARENRDAMD-IHLTTENLAELDRHFPPPRRK----

General information: TITO was launched using: RESULT: Template: 5C7H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1463 32063 21.92 122.38 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : 21.92 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.484

(partial model without unconserved sides chains): PDB file : Tito_5C7H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5C7H-query.scw PDB file : Tito_Scwrl_5C7H.pdb: