Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIMKMTHLNMKDFNKPNEPFVVFGRMIPAFENGVWTYTEERFSKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRI--KIRSNWNGYALIE-DIAVAKDYRKKGVGTA-LLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDTMLYSNFPTANEIAIFWYYKF 2PSW Chain:A ((2-156)) ---------------SKGSRIELGDVTPHNIKQLKRLNQVIFPVSYNDKFYKDVL------EVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGFEIIETKKNYYKRIEPADAHVLQKNLK-

General information: TITO was launched using: RESULT: Template: 2PSW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 659 -55511 -84.24 -367.62 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -84.24 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.228

(partial model without unconserved sides chains): PDB file : Tito_2PSW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2PSW-query.scw PDB file : Tito_Scwrl_2PSW.pdb: