Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSRVTLSRYLIEQTRSHNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVMSNEILLEANEWAGNLAGMASEEMDHPYQIPGRYPKGAYLLVFDPLDGSSNIDVNVSVGTIFSVLRCPNEYLNQNDTLREEAFLQPGTTQVAAGYAIYGPQTMLMLTLGNGVKGFTLDRELGSFVLTHDNISVPESTAEFAINMSNQRHWEAPVKRYVEELLAGKEGPLGKN--YNMRWIASMVADVHRILTRGGVFMYPRDAREPEKPGKLRLMYEANPMSFIIEQAGGAATNGTQRILDIKPENLHQRVAVFLGSKQEVERITGYHAE 4H46 Chain:A ((11-327)) ---VTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGS--------KKLDVLSNDLVINVLKSSFATCVLVSEE-DKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYR-----KNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQR----KKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPK--GKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTEL------

General information: TITO was launched using: RESULT: Template: 4H46.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -165872 for 2650 contacts (-62.6/contact) + 2D Compatibility (PS) -33092 + (NN) -17920 + (LL) 1612 1D Compatibility (HY) -30000 + (ID) 6350 Total energy: -251622.0 ( -94.95 by residue) QMean score : 0.515

(partial model without unconserved sides chains): PDB file : Tito_4H46.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4H46-query.scw PDB file : Tito_Scwrl_4H46.pdb: