Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVREAAMLHIKEGLEQEFEDAFRQAAPIISGMKGYITHSLSKCMEETHKYLLLVEWETLEDHTEGFRGSSEYQEWKA----LLHRFYTPFPTVEHFQDV---- 1IUJ Chain:A ((1-102)) MFVTMNRIPVRPEYAEQFEEAFRQRARLVDRMPGFIRNLVLRPKNPGDPYVVMTLWES-EEAFRAWTESPAFKEGHARSGTLPKEAFLGPNRLEAFEVVLDSE

General information: TITO was launched using: RESULT: Template: 1IUJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 331 -31348 -94.71 -333.48 target 2D structure prediction score : 0.38 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -94.71 2D Compatibility (Sec. Struct. Predict.) : 0.38 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.431

(partial model without unconserved sides chains): PDB file : Tito_1IUJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1IUJ-query.scw PDB file : Tito_Scwrl_1IUJ.pdb: