Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -MNKYEIIANEMRNRIKNNVYPIDQPI-PDEVSLAKEFNSSRMTMKRALDNLVAEGLLFRKRGHGTFIIQSAIQDDHVHVVSNEILGLTNL-LKD-KKIKSKVIQFEVQFPTEEVAAHLSI-DQKTPVYYVVRLRIVEGEPYVLEKTYMPTHLIPGINDDVLHDSIYNHITNVLQLKIAGTHRKIRACKSDHIDQQHL-GCKQDDPILEVEHVGFLDTGI-PFEYSFSRHRHDKFVVTSVNIRR 3EDP Chain:A ((7-236)) KKPLFEVIASKIKDSINRDEY---KTGMPNETALQEIYSSSRTTIRRAVDLLVEEGLVVRKNGVGLYVQPKLTAQNILE------------MTGVMKNLKKDIKDFYIRKAGKFYAEIF-GMKENELVYSIKFVQKSE-HGATLDRLILPLGLYPDLQAKDFQIINIIELVNSGKYKLFELEQELQLILAG-NEQIKNMHLNENDPVFKLSSVFYAE-NDMPIAIQYHYEDAESTKYVVDFN--

General information: TITO was launched using: RESULT: Template: 3EDP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 960 -62119 -64.71 -287.59 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -64.71 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.485

(partial model without unconserved sides chains): PDB file : Tito_3EDP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3EDP-query.scw PDB file : Tito_Scwrl_3EDP.pdb: