Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKHRDSIEDLYRQYYQEILNYLFRRTHHLETAKDLAQDTFVKALNGLASFRG--HSSIRTWLYTIAHHTFINWYRRDVKYQFTEIS-----------------------KNEGL--------------------------T-Q--------------T-TYDQPEQYLSRTVKSETLRQELLKLKDQHQSVLILREF----QELSYEEIAEILGWSLSKVNTTLHRARLELKKNMTKSREEERI 2A6H Chain:F ((180-414)) --GEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPTYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDEHLPSPVDAATQSLLSEELEKALSKLSEREAMVLKLRKGLIDG-----EEVGAFFGVTRERIRQIENKALRKLKYHESR-------

General information: TITO was launched using: RESULT: Template: 2A6H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain F - contact count / total energy / energy per contact / energy per residue : 402 -36566 -90.96 -229.97 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain F : 0.66 3D Compatibility (PKB) : -90.96 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.513

(partial model without unconserved sides chains): PDB file : Tito_2A6H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2A6H-query.scw PDB file : Tito_Scwrl_2A6H.pdb: