Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRF-LPRELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQGFN----LKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVL--QGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSF----PTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST 2YIT Chain:A ((8-278)) -----LRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISK----------LNVETEIEILKKLNHPCIIKIKNFFDAEDYYI--VLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETS--LMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDE

General information: TITO was launched using: RESULT: Template: 2YIT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -136747 for 1780 contacts (-76.8/contact) + 2D Compatibility (PS) -26431 + (NN) -12697 + (LL) 1468 1D Compatibility (HY) -20800 + (ID) 4850 Total energy: -200057.0 ( -112.39 by residue) QMean score : 0.427

(partial model without unconserved sides chains): PDB file : Tito_2YIT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YIT-query.scw PDB file : Tito_Scwrl_2YIT.pdb: