Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKFAVIVLPGSNCDIDMYHAVKDELGHEVEYVWHEE--TSL--DGFDGVLIPGGFSYGDYLRCGAIARFANIMPAVKQAAAEGKPVLGVCNGFQILQELGLLPGAMRRNKDLKFICRPVELIVQ---------------------------NDETLFTASYEKGESITIPVAHGEGNFYCDDETLATLKENNQIAFTYGSNINGSVSDIAGVVNEKGNVLGMMPHPERAVDELLGSADGLKLFQSIV-KNWRETHVTTA 3UOW Chain:A ((8-260)) DKILVLNFGSQY-FHLIVKRLNNI-KIFSETKDYGVELKDIKDMNIKGVILSGGPYSVTEA---GSPHL--KKEVFEYFLEKKIPIFGICYGMQEIAVQM---NGEVKKSK-TSEYGCTDVNILRNDNINNITYCRNFSSAMDLYSNYKLMN--CCLFENIKS-DITTVWMNHNDEVTKIP---------ENFYLVSS--SENCL---ICSIYNKEYNIYGVQYHPEVYESL-DG----ELMFYNFAYNICKC------

General information: TITO was launched using: RESULT: Template: 3UOW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1129 -122365 -108.38 -650.88 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -108.38 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.372

(partial model without unconserved sides chains): PDB file : Tito_3UOW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UOW-query.scw PDB file : Tito_Scwrl_3UOW.pdb: