Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKWMCSICCAAVLLAGGAAQAEAVPNEPINWGFKRSVNHQPPDAGKQLNSLIEKYDAFYLGNTKEKTIYLTFDNGYENGYTPKVLDVLKKHRVTGTFFVTGHFVK--------DQPQLIKRMSDEGHIIGNHSFHHPDLTT---------------------------KTADQIQDELDSVNEEVYKITGKQ---DNLYLRPPRGVFSE---------------------------------------YVLKETKRLGYQTVFWSVAF--VDWKINNQK----GKKYAYDHM---I----------------------KQAHPGAIYLLHTVSR----------DNAEALDDAITDLKKQGYTFKSIDDLMFEKEMRLPSL 3WX7 Chain:A ((2-310)) ----------------------------------------------------------------KGTIYLTFDDGPIN-ASIDVINVLNQEEVKATFYFNAWHLDGIGDENEDRALEALKLALDSGHIVANHSYDHMVHNCVEEFGPNSAAECNATGDHQINSYQDPAYDASMFAENLSVLEKYLPNITSYPNYKANEFARLPYTNGWRVTKDFKADGLCATSDDLKPWEPGYACDTANPSNSVKAAIAVQNILANNGYQTHGWDVDWAPENWGIAMPANSLTEAEPFLGYVDSALNTCAPTTINPINSKAQEFPCGTPLHADKVIVLTHEFLFEDGKRGMGATQNLPKLTKFIQLAKQAGYVFDTMDNYTPNW-------

General information: TITO was launched using: RESULT: Template: 3WX7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 956 -95876 -100.29 -501.97 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -100.29 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.553

(partial model without unconserved sides chains): PDB file : Tito_3WX7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3WX7-query.scw PDB file : Tito_Scwrl_3WX7.pdb: