Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----MTLIILEGPDCCFKSTVAAKLSKELKYPIIKGSSFELAKSGNEKLFEHFNKLADEDNVIIDRFVYSNLVYAKKFKDYSILT----ERQLRFIEDKIKAKAKVVYLHADPSVIKKRLRVRGDEYIEGKDIDSILELYREVMSN-AGLHTYSWDTGQWSSDEIAKDIIFLVE- 1KNQ Chain:A ((3-173)) TTNHDHHIYVLMGVSGSGKSAVASEVAHQLHAAFLDGDFLH--PRRNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKVSLIVCSALKKHYRDLLREGNPNLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETDVLVVDIDQ---PLEGVVASTIEVIKK

General information: TITO was launched using: RESULT: Template: 1KNQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 714 37149 52.03 232.18 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : 52.03 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.487

(partial model without unconserved sides chains): PDB file : Tito_1KNQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KNQ-query.scw PDB file : Tito_Scwrl_1KNQ.pdb: